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In a very new review, we claimed the identification and the characterization of a brand new atypical opioid receptor with exceptional adverse regulatory properties in direction of opioid peptides.1 Our effects confirmed that ACKR3/CXCR7, hitherto called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a wide-spectrum scaveng

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When it is actually unknown no matter if other unidentified interactions are happening in the receptor that contribute to its effects, the receptor performs a role like a damaging down regulator of endogenous opiate stages through scavenging activity. This drug-receptor conversation provides an alternative choice to manipulation in the classical op